Inferring protein domains associated with drug side effects based on drug-target interaction network
نویسندگان
چکیده
منابع مشابه
Relating drug–protein interaction network with drug side effects
MOTIVATION Identifying the emergence and underlying mechanisms of drug side effects is a challenging task in the drug development process. This underscores the importance of system-wide approaches for linking different scales of drug actions; namely drug-protein interactions (molecular scale) and side effects (phenotypic scale) toward side effect prediction for uncharacterized drugs. RESULTS ...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2013
ISSN: 1752-0509
DOI: 10.1186/1752-0509-7-s6-s18